Carbetocin to Prevent Uterine Contraction and Postpartum Hemorrhage Featured Image

Carbetocin ho Thibela ho Honyela ha Uterine le ho tsoa mali ka mor'a ho pepa

Tlhaloso e Khutšoanyane:

Lebitso: CARBETOCIN

Nomoro ea CAS: 37025-55-1

Mokhoa oa molek'hule: C45H69N11O12S

Boima ba molek'hule: 988.17

Nomoro ea EINECS: 253-312-6

Potoloho e khethehileng: D -69.0° (c = 0.25 ho 1M acetic acid)

Sebaka se belang: 1477.9±65.0 °C (Ho Boletsoe esale pele)

Boima: 1.218±0.06 g/cm3(E boletsoeng esale pele)

Maemo a polokelo: -15°C

Foromo: phofo

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lintlha tsa Sehlahisoa

Lebitso	CARBETOCIN
Nomoro ea CAS	37025-55-1
Mokhoa oa limolek'hule	Setšoantšo sa C45H69N11O12S
Boima ba molek'hule	988.17
Nomoro ea EINECS	253-312-6
Ho potoloha ho itseng	D -69.0° (c = 0.25 ho 1M acetic acid)
Ntho e belang	1477.9±65.0 °C (E boletsoeng esale pele)
Botenya	1.218±0.06 g/cm3(E boletsoeng esale pele)
Maemo a polokelo	-15°C
Sebopeho	phofo

Litlhaloso tse tšoanang

BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2, (SULFIDEBODBETWEENBUTYL-4-YLANDCYS);BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2TRIFLUOROACETATESALT;(BUTYRYL1, TYR(ME)2) -1-CARBAOXYTOC INTRIFLUOROACETATESALT;(BUTYRYL1, TYR(ME)2) -OXYTOCIN;(BUTYRYL1,TYR(ME)2)-OXYTOCINTRIFLUOROACETATESALT;CARBETOCIN;CARBETOCINTRIFLUOROACETATESALT;(2-O-METHYLTYROSINE)-DE-AMINO-1-CARBAOXYTOCIN

Mosebetsi oa likokoana-hloko

Carbetocin, analog ea oxytocin (OT), ke agonist ea oxytocin receptor e nang le Ki ea 7.1 nM.Carbetocin e na le kamano e phahameng (Ki = 1.17 μM) bakeng sa chimeric N-terminus ea oxytocin receptor.Carbetocin e na le monyetla oa ho etsa lipatlisiso tsa mali a tsoang ka mor'a ho pepa.Carbetocin e ka phunyeletsa mokoallo oa mali le boko 'me e na le ts'ebetso e kang ea antidepressant ka ho kenya li-receptor tsa oxytocin ho CNS.

Mosebetsi

Carbetocin ke analoge ea maiketsetso ea nako e telele ea oxytocin 8-peptide e nang le litšobotsi tsa agonist, 'me thepa ea eona ea bongaka le ea meriana e tšoana le ea oxytocin ea tlhaho.Joalo ka oxytocin, carbetocin e tlama ho li-receptor tsa lihomone tsa mesifa e boreleli ea uterine, e bakang ho honyela ho hoholo ha popelo, ho eketsa makhetlo a eona le ho eketsa molumo oa popelo motheong oa likhohlano tsa pele.Maemo a li-receptor tsa Oxytocin ka popelong a tlase maemong ao e seng moimana, a eketseha nakong ea bokhachane, 'me a phahama nakong ea ho pepa.Ka hona, carbetocin ha e na phello ho lesea le se nang moimana, empa e na le phello e matla ea "contractile" ea uterine ka popelong ea moimana le popelong e sa tsoa hlahisoa.

Fetola Litaolo

Liphetoho li laoloa ho latela mokhoa.Ho ipapisitsoe le tšusumetso le kotsi le ho teba, liphetoho li aroloa e le tse kholo, tse nyane le tsa Sebaka.Liphetoho tsa sebaka sa marang-rang li na le tšusumetso e fokolang ho polokeho le boleng ba sehlahisoa, ka hona ha li hloke tumello le tsebiso ho moreki;Liphetoho tse nyane li na le phello e itekanetseng polokehong le boleng ba sehlahisoa, 'me li hloka ho tsebisa moreki;Liphetoho tse kholo li na le tšusumetso e phahameng holim'a polokeho le boleng ba sehlahisoa, 'me li hloka tumello ke moreki.

Ho latela ts'ebetso, taolo ea phetoho e qala ka ts'ebeliso ea phetoho eo ho eona lintlha tsa phetoho le tse utloahalang bakeng sa phetoho li hlalosoang.Tlhahlobo e etsoa ka mor'a kopo, e etsoang ke mafapha a amehang a taolo ea phetoho.Ho sa le joalo, taolo ea phetoho e arotsoe ka boemo bo boholo, boemo ba kakaretso le boemo bo nyane.Ka mor'a tlhahlobo e nepahetseng hammoho le lihlopha, taolo eohle ea phetoho ea boemo e lokela ho amoheloa ke QA Manager.Taolo ea phetoho e etsoa ka mor'a tumello ho latela moralo oa ts'ebetso.Taolo ea phetoho e qetella e koetsoe ka mor'a hore QA e tiise hore taolo ea phetoho e sebelisitsoe ka nepo.Haeba ho kenyelletsa tsebiso ea moreki, moreki o lokela ho tsebisoa ka nako kamora hore taolo ea phetoho e amoheloe

E fetileng: Atosiban Acetate E Sebelisitsoe ho Tsoaloa Pele ho Pele ho Nako

E 'ngoe: Cetrorelix Acetate ho Thibela Ovulation Pele ho Nako 120287-85-6

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