Carseetocin ho thibela tumellano ea portine le postpartum hemorrhage
Lintlha tsa sehlahisoa
| Lebitso | CarBerocin |
| Nomoro ea CAS | 37025-55-1 |
| Foromo ea limolecular | C45h69n11o12s |
| Boima ba Molecular | 988.17 |
| Nomoro ea Einecs | 253-312-6 |
| Ho potoloha ka ho khetheha | D -69.0 ° (C = 0.25 ho 1m acetic acid) |
| Poleft Point | 1477.9 ± 65.0 ° C (e boletsoeng esale pele) |
| Letsoalo | 1.218 ± 0.06 g / cm3 (e boletsoeng esale pele) |
| Maemo a polokelo | -15 ° C |
| Foromo | phofo |
Synonyms
Buyryl-tyr (Me)-cln-cln-cys-cys-gy-gly-na2, (sulfidebondbenryrylryl-4-ylandcys); Buyryl-tyr (Me)-cln-cln-cys-cys-gy-gly-nh2ttrualt; (Buyryl1, TYR (TYR (nna) 2) -1-carbaoxluoc enterifluomacelt; (Buyryl1, TYR (nna) 2) -ooxtocin; . Carbetocin; CarbecintrifluoAcemal; (2-o-methyltyrorine) -de-amino-1-carbaoxtocin
Ts'ebetso ea Bohlokoa
CarBetocin, oxelactocin (ot), ke axotocin receptor Rector conpsonist e nang le ki ea 7.1 nm. Carbetocin o na le boits'oaro bo phahameng (ki = 1.17 μm) bakeng sa chimic n-hasptor ea oxytocin. Carbetocin e na le monyetla oa postpartum hemorrhage. Carbetocin e ka kenella ka har'a tšitiso ea mali le e thibelang lintho tse thibetsoeng ke ho kenya tšebetsong li-receptors tsa oxytocin ka li-cNS.
Ts'ebetso
Carbetocin ke ena ea maiketsetso ea nako e telele ea oxytocin 8-Petide ka thepa ea eona ea lefutso, 'me thepa ea eona ea bongaka e etsahalang ka tlhaho e etsahala oxytocin e etsahalang ka tlhaho. Joalo ka oxytocin, Carbetocin e tlama mesifa ea li-hormone ea molomo, ea eketsa likhakanyo tsa lithako, tse ntseng li eketseha ka tonera mabapi le tšitiso ea pele. Maemo a polokelo ea oxytocin ka popelong a tlase ho naha eo e sa imang, ho eketsa nakong ea kemolo, le tlhoro nakong ea mosebetsi. Ka hona, Carbetocin ha e na tšusumetso polelong e sa ima, empa e na le phello ea konteraka ea konteraka ea postrine ho ipapi ea moimana ebe u fana ka sehlooho se sa tsoa hlaha.
Fetola taolo
Liphetoho li laoloa ho latela ts'ebetso. Ho latela tšusumetso le kotsi le ho teba, liphetoho li khethollotsoe e le kholo, e nyane le sebaka sa marang-rang. Liphetoho tsa sebaka se na le tšusumetso e nyane polokelong le boleng ba sehlahisoa, ka hona ha u hloke tumello le tsebiso ho moreki; Liphetoho tse nyane li na le phello e itekanetseng polokelong le boleng ba sehlahisoa, 'me u hloka ho tsebisa moreki; Liphetoho tse kholo li na le tšusumetso e phahameng polokelong le boleng ba sehlahisoa, 'me u hloka tumello ke moreki.
Ho latela ts'ebetso, taolo ea phetoho e qala ka ts'ebeliso ea phetoho ea lintlha le kelello bakeng sa phetoho e hlalositsoeng. Tlhaloso e etsoa ka mor'a kopo, e etsoang ke ho fetola mafapha a amehang. Ho sa le joalo, taolo ea phetoho e khethoa hore e be maemong a maholo, boemo bo akaretsang le bo fokolang. Kamora tlhahlobo e nepahetseng hammoho le ts'ebetso, taolo eohle ea phetoho e lokela ho amoheloa ke molaoli oa QA. Taolo ea phetoho e bolaoa kamora tumello ho latela moralo oa tšebetso. Taolo ea phetoho e se e koetsoe kamora QA e tiisa taolo ea phetoho e kentsoeng ka nepo. Haeba ho kenyelletsa tsebiso ea moreki, moreki o lokela ho tsebisoa ka nako e telele kamora taolo ea phetoho
