Peptide APIs
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MOTS-C
MOTS-C API e hlahisoa tlas'a maemo a thata a kang a GMP ho sebelisoa theknoloji e tiileng ea "peptide synthesis" (SPPS) ho netefatsa boleng ba eona bo phahameng, bohloeki bo phahameng le botsitso bo phahameng bakeng sa lipatlisiso le tšebeliso ea phekolo.
Likarolo tsa Sehlahisoa:Bohloeki ≥ 99% (e tiisitsoe ke HPLC le LC-MS),
Endotoxin e tlase le lintho tse setseng tsa solvent,
E hlahisitsoe ho latela liprothokholo tsa ICH Q7 le GMP,
E ka fihlela tlhahiso e kholo, ho tloha ho li-batch tsa R&D tsa boemo ba milligram ho isa phepelong ea khoebo ea boemo ba gram le kilogram. -
Ipamorelin
Ipamorelin API e lokiselitsoe ka mokhoa o phahameng oa ** solid phase peptide synthesis process (SPPS) ** mme e etsa tlhahlobo e tiileng le tlhahlobo ea boleng, e loketseng tšebeliso ea pele ea liphaephe lipatlisisong tsa saense le nts'etsopele le lik'hamphani tsa meriana.
Likarolo tsa sehlahisoa li kenyelletsa:
Bohloeki ≥99% (tlhahlobo ea HPLC)
Ha ho na endotoxin, solvent e tlase e setseng, tšilafalo ea tšepe e tlase
Fana ka sete e feletseng ea litokomane tsa boleng: COA, tlaleho ea boithuto ba botsitso, tlhahlobo ea mahlaseli a litšila, joalo-joalo.
Phepelo ea boemo ba gram ~ kilogram-level -
Pulegone
Pulegone ke monoterpene ketone ea tlhaho e fumanehang ka har'a oli ea bohlokoa ea mefuta e kang pennyroyal, spearmint le peppermint. E sebelisoa e le setlolo sa tatso, motsoako oa monko o monate, 'me e bohareng ba meriana le metsoako ea lik'hemik'hale. Pulegone API ea rona e etsoa ka mekhoa e hloekisitsoeng ea ho ntša le ho hloekisa ho netefatsa bohloeki bo phahameng, bo tsitsitseng, le ho latela melao e nepahetseng ea polokeho le boleng.
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Etelcalcetide
Etelcalcetide ke calcimimetic ea maiketsetso ea peptide e sebelisetsoang ho phekola hyperparathyroidism ea bobeli (SHPT) ho bakuli ba nang le lefu la liphio le sa foleng (CKD) ka hemodialysis. E sebetsa ka ho kenya tšebetsong calcium-sensing receptor (CaSR) liseleng tsa parathyroid, kahoo e theola maemo a parathyroid hormone (PTH) le ho ntlafatsa metabolism ea diminerale. Etelcalcetide API ea rona ea bohloeki bo phahameng e etsoa ka "solid-phase peptide synthesis" (SPPS) tlas'a maemo a lumellanang le GMP, a loketseng ho etsoa ka ente.
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Bremelanotide
Bremelanotide ke peptide ea maiketsetso le melanocortin receptor agonist e ntlafalitsoeng bakeng sa kalafo ea "hypoactive sex desire disorder" (HSDD) ho basali ba premenopausal. E sebetsa ka ho kenya tšebetsong MC4R tsamaisong ea methapo e bohareng ho matlafatsa takatso ea thobalano le ho tsoheloa. Bremelanotide API ea rona ea bohloeki bo phahameng e etsoa ka solid-phase peptide synthesis (SPPS) tlas'a maemo a thata a boleng, a loketseng ho etsoa ka ente.
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Etelcalcetide Hydrochloride
Etelcalcetide Hydrochloride ke e entsoeng ka peptide e thehiloeng calcimimetic agent e sebelisoang bakeng sa phekolo ea hyperparathyroidism ea bobeli (SHPT) ho bakuli ba nang le lefu la liphio le sa foleng (CKD) ka hemodialysis. E sebetsa ka ho kenya li-receptors tsa calcium-sensing (CaSR) karolong ea parathyroid, kahoo e fokotsa maemo a parathyroid hormone (PTH) le ho ntlafatsa tekanyo ea calcium-phosphate. Etelcalcetide API ea rona e hlahisoa ka motsoako oa peptide ea bohloeki bo phahameng 'me e lumellana le litekanyetso tsa boleng ba machaba bakeng sa lihlahisoa tse entoang tsa boemo ba meriana.
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Desmopressin Acetate ho Phekola Bohareng ba Diabetes Insipidus
Lebitso: Desmopressin
Nomoro ea CAS: 16679-58-6
Mokhoa oa molek'hule: C46H64N14O12S2
Boima ba molek'hule: 1069.22
Nomoro ea EINECS: 240-726-7
Potoloho e khethehileng: D25 +85.5 ± 2° (e baloang bakeng sa peptide ea mahala)
Boima: 1.56±0.1 g/cm3(E boletsoeng esale pele)
Nomoro ea RTECS: YW9000000
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Eptifibatide bakeng sa Phekolo ea Acute Coronary Syndrome 188627-80-7
Lebitso: Eptifibatide
Nomoro ea CAS: 188627-80-7
Mokhoa oa molek'hule: C35H49N11O9S2
Boima ba molek'hule: 831.96
Nomoro ea EINECS: 641-366-7
Boima: 1.60±0.1 g/cm3(E boletsoeng esale pele)
Maemo a polokelo: E koetsoe ka sehatsetsing, ka tlas'a -15°C
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Terlipressin Acetate bakeng sa Esophageal Variceal Bleeding
Lebitso: N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
Nomoro ea CAS: 14636-12-5
Mokhoa oa molek'hule: C52H74N16O15S2
Boima ba molek'hule: 1227.37
Nomoro ea EINECS: 238-680-8
Sebaka se belang: 1824.0±65.0 °C (Ho Boletsoe esale pele)
Boima: 1.46±0.1 g/cm3(E boletsoeng esale pele)
Maemo a polokelo: Boloka sebakeng se lefifi, sebakeng se sa tsitsang, Boloka ka sehatsetsing, ka tlas'a -15°C.
Acidity coefficient: (pKa) 9.90±0.15 (E boletsoeng esale pele)
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Teriparatide Acetate API for Osteoporosis CAS NO.52232-67-4
Teriparatide ke 34-peptide ea maiketsetso, karolo ea 1-34 ea amino acid ea hormone ea motho ea parathyroid PTH, e leng sebaka sa N-terminal se sebetsang ka biologically sa 84 amino acid endogenous parathyroid hormone PTH. Thepa ea 'mele le likokoana-hloko ea sehlahisoa sena e tšoana hantle le ea endogenous parathyroid hormone PTH le bovine parathyroid hormone PTH (bPTH).
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Atosiban Acetate E Sebelisitsoe ho Tsoaloa Pele ho Pele ho Nako
Lebitso: Atosiban
Nomoro ea CAS: 90779-69-4
Mokhoa oa molek'hule: C43H67N11O12S2
Boima ba molek'hule: 994.19
Nomoro ea EINECS: 806-815-5
Sebaka se belang: 1469.0±65.0 °C (Ho Boletsoe esale pele)
Boima: 1.254±0.06 g/cm3(E boletsoeng esale pele)
Maemo a polokelo: -20°C
Sollubility: H2O: ≤100 mg/mL
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Carbetocin ho Thibela ho Honyela ha Uterine le ho tsoa mali ka mor'a ho pepa
Lebitso: CARBETOCIN
Nomoro ea CAS: 37025-55-1
Mokhoa oa molek'hule: C45H69N11O12S
Boima ba molek'hule: 988.17
Nomoro ea EINECS: 253-312-6
Potoloho e khethehileng: D -69.0° (c = 0.25 ho 1M acetic acid)
Sebaka se belang: 1477.9±65.0 °C (Ho Boletsoe esale pele)
Boima: 1.218±0.06 g/cm3(E boletsoeng esale pele)
Maemo a polokelo: -15°C
Foromo: phofo