Eptifibatide bakeng sa Phekolo ea Acute Coronary Syndrome 188627-80-7
Lintlha tsa Sehlahisoa
| Lebitso | Eptifibatide |
| Nomoro ea CAS | 188627-80-7 |
| Mokhoa oa limolek'hule | Setšoantšo sa C35H49N11O9S2 |
| Boima ba molek'hule | 831.96 |
| Nomoro ea EINECS | 641-366-7 |
| Botenya | 1.60±0.1 g/cm3(E boletsoeng esale pele) |
| Maemo a polokelo | E koetsoe ka sehatsetsing, ka tlas'a -15 ° C |
Litlhaloso tse tšoanang
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6- (Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteineamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2 (DISULFIDEBRIDGE,MPA1-CYS6).
Mohanyetsi oa Platelet Glycoprotein
Etifibatide (integrilin) ke mofuta o mocha oa polypeptide platelet glycoprotein IIb/IIIa receptor antagonist, e thibelang ho bokellana ha platelet le thrombosis ka ho thibela tsela ea ho qetela e tloaelehileng ea ho bokellana ha platelet.Ha e bapisoa le monoclonal antibody abciximab, eptifibatide e na le matla a matla, a tobileng le a tobileng ho GPIIb/IIIa ka lebaka la ho ba teng ha sebaka se le seng sa amino acid - lysine ho nkela arginine sebaka.Ka hona, e lokela ho ba le phello e ntle ea phekolo kalafong ea ho kenella ea lefu le matla la coronary.Platelet glycoprotein IIb/IIIa receptor antagonists lithethefatsi li entsoe haholo, 'me hajoale ho na le mefuta e 3 ea litokisetso tse ka sebelisoang litsing tsa bongaka tsa machaba, abciximab, eptifibatide le tirofiban.).Ho na le phihlelo e fokolang ea tšebeliso ea li-platelet glycoprotein GPIIb/IIIa li-receptor antagonists Chaena, 'me lithethefatsi tse teng le tsona li fokotsehile haholo.Ke sethethefatsi se le seng feela, tirofiban hydrochloride, se teng 'marakeng.Ka hona, ho ile ha etsoa platelet glycoprotein IIb e ncha./IIIa bahanyetsi ba li-receptor ba bohlokoa.Domestic eptifibatide ke sehlahisoa sa maiketsetso se hlahisoang ke Chengdu Sino Biological Products Co., Ltd.
Karolelano
Classification of Antiplatelet Aggregation Drugs
Lithethefatsi tsa ho kopanya li-antiplatelet li ka aroloa ka likarolo tse tharo: 1. Cyclooxygenase-1 (COX-1) inhibitors, tse kang aspirin.2. Thibela platelet aggregation e bakoang ke adenosine diphosphate (ADP), e kang clopidogrel, prasugrel, cangrelor, ticagrelor, joalo-joalo 3. Platelet glycoprotein Ⅱb/Ⅲa receptor antagonists, tse kang abciximab, eptifibatide, joalo-joalo. prostaglandin EP3 receptor inhibitors, likaroloana tsa lik'hemik'hale tse sa tsoa etsoa le li-extracts tse sebetsang tse tsoang meriana ea setso ea Sechaena.
