Terlipressin Acetate bakeng sa esophagal ho tsoa mali
Lintlha tsa sehlahisoa
| Lebitso | N- (N- Glycylglycyl) Glycyl) -8-L-L-L-L-L-L-L-L-L-L-L-L-lystinevapresn |
| Nomoro ea CAS | 14636-12-5 |
| Foromo ea limolecular | C52h74n16O15s2 |
| Boima ba Molecular | 1227.37 |
| Nomoro ea Einecs | 238-680-8 |
| Poleft Point | 1824.0 ± 65.0 ° C (esale pele) |
| Letsoalo | 1.46 ± 0.1 g / cm3 (e boletsoeng esale pele) |
| Maemo a polokelo | Leitha sebakeng se lefifi, sepakapaka se setle ho sepakapaka, lejoe ka lahliszer, tlas'a Celsies C.5 ° C. |
| Acidity cormety | (pka) 9.90 ± 0.15 (e boletsoeng esale pele) |
Synonyms
[N-α-Triglysl-8-Lysine] -vastine. -Vasopresn; 130: PN: Wo201003320D: 171claimdprotein; 1-Triglycyl-8-Lystinevasopressin; Ncy-glycyl-glycyl-glycyl- [8-lysine] -vasopresn; Ncy-glycyl-glycyl-glycyl-glycyl-lycyl-glycyl-li-vasaprestin; Ncy-glycylilycylcylcyl-vasapressin; Ncy-gly-gly-gly-gly-8-Lys-vasopressin; Terliprosin, Terlipresn, Terlipressina, Terlipresninum.
Tlhaloso
Terlipresnin, eo lebitso la lik'hemik'hale ea hae e tlotsang Vasopresn, ke boithabiso bo bocha ba vasopresn. Ke mofuta oa prodrug, e leng e sa sebetseng ka boeona. E entsoe ke Amonopepdidase ho VIVO ho lokolla "leseli le sebetsang ka mor'a ho tlosa masala a mararo a ho tlosa masala a mararo a ho tlosa n-terminus. Ka hona, terlipursnin e sebetsa e le sepotla sa polokelo e fetisang li-pesineskin ka lebelo le tsitsitseng.
Phello ea litlhare tsa Terlipressin e ho fokotsa ho phalla mali le ho fokotsa mali, ka ho etsa molumo oa mali, joalo ka khatello ea mali le khatello ea mali. Ka lehlakoreng le leng, e ka boela ea fokotsa phello ea ho tsepamisa mohopolo, ka tsela eo e ne e eketsa ho phalla mali le ho ntlafatsa tšebetso ea remanal le ho eketsa mothapo ea hepatorenal. Hajoale terlipskin e le eona feela sethethefatsi se ka ntlafatsang boemo ba pholoholi ba bakuli le esophagage. E ne e sebelisoa haholo ka mokhoa oa bongaka oa hemorrhage. Ntle le moo, Terlipstin le eena o sebelisitsoe ka katleho ka sebete le monoana. Ka kakaretso, ho ka etsahala hore u be karolo e ntle ea ho phomola le ho tsosa pelo le pordiopulmonary. Ha ho bapisoa le vasopresn, e na le phello e telele, ha e etsetse mathata a kotsi, 'me ho bonolo ho sebelisa tlhokomelo ea pelo, e loketseng tlhokomelo e matla le e tšoaeang. Pholoso le kalafo ea bakuli ba kulang haholo.
