Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU ke molek'hule ea maiketsetso ea lipidated linker e etselitsoeng phano ea lithethefatsi le li-antibody-drug conjugates (ADCs). E na le mohatla oa stearoyl (Ste) hydrophobic, γ-glutamyl targeting motif, AEEA spacers bakeng sa ho feto-fetoha ha maemo, le sehlopha sa OSu (NHS ester) bakeng sa ho kopanya hantle.

 
Lipatlisiso le Lisebelisoa:

E sebelisoa molemong oa tlhahiso ea lihlahisoa tse lebisitsoeng le moralo oa nanocarrier

E matlafatsa tšebelisano ea lisele tsa lisele le ho sebelisoa ha lithethefatsi

E thusa ho ikamahanya le sebaka se ikhethileng sa moputso ho li-peptide, li-antibodies, kapa bajari

Likarolo tsa Sehlahisoa (Gentolex Group):

Bohloeki bo phahameng, bo itokiselitseng ho kopanya NHS ester

E loketse bioconjugation le lipatlisiso tse reriloeng tsa phano

Ste-γ-Glu-AEEA-AEEA-OSU e loketse bakeng sa ntshetsopele ea tsamaiso ea phano ea lithethefatsi e nepahetseng.