Peptide APIs
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Tirzepatide
Tirzepatide ke agonist e ncha ea li-agonists tsa GIP le GLP-1 receptors, e etselitsoeng kalafo ea lefu la tsoekere la mofuta oa 2 le botenya. Joalo ka "twincretin" ea sehlopha sa pele, Tirzepatide e ntlafatsa tlhahiso ea insulin, e hatella ho lokolloa ha glucagon, 'me e fokotsa haholo takatso ea lijo le boima ba' mele. Tirzepatide API ea rona ea bohloeki bo phahameng e entsoe ka lik'hemik'hale, ha e na litšila tse tsoang liseleng tse amohelang baeti, 'me e kopana le litekanyetso tsa taolo ea machaba bakeng sa boleng, botsitso, le scalability.
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Semaglutide
Semaglutide ke GLP-1 receptor agonist ea nako e telele e sebelisetsoang ho phekola lefu la tsoekere la mofuta oa 2 le taolo ea boima bo sa foleng. Semaglutide API ea rona ea bohloeki bo phahameng e hlahisoa ka metsoako ea lik'hemik'hale, e se nang liprotheine tsa lisele tse amohelang le masala a DNA, ho netefatsa hore biosafety e babatsehang le boleng bo tsitsitseng. E lumellana le litataiso tsa FDA, sehlahisoa sa rona se kopana le meeli e thata ea ho se hloeke 'me se tšehetsa tlhahiso e kholo.
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Retatrutide
Retaglutide ke sethethefatsi se secha sa dipeptidyl peptidase-4 (DPP-4) inhibitor class hypoglycemic se ka thibelang ho senyeha ha glucagon-like peptide-1 (GLP-1) le glucose e itšetlehileng ka insulin-releasing polypeptide (GIP) ka enzyme ea DPP-4 ka maleng le maling, ka ho lelefatsa ts'ebetso ea bona ea insulin, ho lelefatsa ts'ebetso ea bona ea "insulin". basal level ea insulin e itima lijo, ha e ntse e fokotsa tlhahiso ea glucagon ka lisele tsa pancreatic α, ka tsela eo e laola ka katleho tsoekere ea mali ea postprandial. E sebetsa hantle ho latela phello ea hypoglycemic, mamello le ho latela melao.
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Liraglutide Anti-Diabetics bakeng sa Taolo ea Tsoekere ea Mali CAS NO.204656-20-2
Sejo se sebetsang:Liraglutide (analogue ea glucagon-like peptide-1 (GLP-1) e hlahisoang ke tomoso ka theknoloji ea ho kopanya liphatsa tsa lefutso).
Lebitso la lik'hemik'hale:Arg34Ls26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37]
Lisebelisoa tse ling:Disodium Hydrogen Phosphate Dihydrate, Propylene Glycol, Hydrochloric Acid le/kapa Sodium Hydroxide (e le pH Adjusters Feela), Phenol, le Metsi a Ente.
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Leuprorelin Acetate e Laola Sephiri sa Li-Hormone tsa Gonadal
Lebitso: Leuprorelin
Nomoro ea CAS: 53714-56-0
Mokhoa oa molek'hule: C59H84N16O12
Boima ba molek'hule: 1209.4
Nomoro ea EINECS: 633-395-9
Potoloho e khethehileng: D25 -31.7° (c = 1 ho 1% acetic acid)
Boima: 1.44±0.1 g/cm3(E boletsoeng esale pele)
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BPC-157
BPC-157 API e sebelisa mokhoa o tiileng oa ho kopanya likarolo (SPPS):
Bohloeki bo phahameng: ≥99% (ho lemoha HPLC)
Masala a litšila a tlase, ha a na endotoxin, ha a na tšilafalo ea tšepe e boima
Ho tsitsa ha sehlopha, ho pheta-pheta ho matla, ts'ebeliso ea boemo ba ente ea tšehetso
Ts'ehetso ea phepelo ea boemo ba gram le kilogram ho fihlela litlhoko tsa mekhahlelo e fapaneng ho tloha ho R&D ho isa indastering. -
CJC-1295
CJC-1295 API e hlahisoa ho sebelisoa thekenoloji ea solid phase peptide synthesis (SPPS) mme e hloekisoa ka ho sebelisa HPLC ho fihlela bohloeki bo phahameng le ho lumellana ha batch-to-batch.
Likarolo tsa Sehlahisoa:Bohloeki ≥ 99%
Li-solvents tse setseng tse tlase le litšepe tse boima
Endotoxin-mahala, tsela e seng ea immunogenic synthesis
Lipalo tse u ka li khethang: mg ho isa ho lik'hilograma
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NAD+
Likarolo tsa API:
Bohloeki bo phahameng ≥99%
Pharmaceutical-grade NAD+
Litekanyetso tsa tlhahiso tse kang GMP
NAD+ API e loketse ho sebelisoa ho li-nutraceuticals, liente, le liphekolo tse tsoetseng pele tsa metabolic.
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Cagrilintide
Cagrilintide ke amylin receptor agonist ea maiketsetso, ea nako e telele, e etselitsoeng ho phekola botenya le mathata a amanang le boima ba 'mele. Ka ho etsisa hormone ea tlhaho ea amylin, e thusa ho laola takatso ea lijo, ho lieha ho tsoa ka mpeng, le ho matlafatsa ho khora. API ea rona ea boleng bo phahameng ea Cagrilintide e hlahisoa ka lik'hemik'hale tsa lik'hemik'hale 'me e kopana le litekanyetso tsa litekanyetso tsa meriana, e leng se etsang hore e loketse ho sebelisoa mefuteng e tsoetseng pele ea ho laola boima ba' mele.
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Tesamorelin
Tesamorelin API e sebelisa theknoloji e tsoetseng pele ea "peptide synthesis" (SPPS) mme e na le lintlha tse latelang:
Bohloeki ≥99% (HPLC)
Ha ho na endotoxin, lirafshoa tse boima, li-solvents tse setseng tse lekiloeng
Tatelano ea amino acid le sebopeho se tiisitsoeng ke LC-MS/NMR
Fana ka tlhahiso e ikhethileng ka ligrama ho isa ho lik'hilograma -
N-Acetylneuraminic Acid(Neu5Ac Sialic Acid)
N-Acetylneuraminic Acid (Neu5Ac), eo hangata e tsejoang e le sialic acid, ke monosaccharide ea tlhaho e amehang mesebetsing ea bohlokoa ea lisele le 'mele ea ho itšireletsa mafung. E bapala karolo ea bohlokoa ho bonts'a lisele, ts'ireletso ea pathogen, le nts'etsopele ea boko.
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Ergothioneine
Ergothioneine ke tlhaho ea tlhaho ea amino acid e nkiloeng ho antioxidant, e ithutoang bakeng sa thepa ea eona e matla ea cytoprotective le e thibelang botsofali. E entsoe ke li-fungus le libaktheria 'me e bokellana ka har'a lisele tse pepesehileng khatellong ea oxidative.
