Cas | 204656-20-20-2 | Foromo ea limolecular | C172H265N43O51 |
Boima ba Molecular | 3751.20 | Ponahalo | Tšoeu |
Boemo ba polokelo | Khanyetso e Khanyang, Ratey Degree | Package | Aluminium Fil Bag / Vial |
Bohloeki | ≥98% | TS'ELISO | Ketane e batang le phaello e pholileng |
Motsoako o sebetsang:
Liraglillede (Analog ea Bilicagoon - Joaloka Petide-1 (GLP-1) e hlahisoang ke tomoso ka theknoloji ea liphatsa tsa lefutso).
Lebitso la lik'hemik'hale:
Arg34lys26- (N-c- (Γ-Glu (γ-Hexadecanoyl)) - GLP-1 [7-37]
Metsoako e meng:
Distiri "hydrogen fysphate"
Mofuta oa 2 oa lefu la tsoekere
Liragllide e ntlafatsa taolo ea tsoekere ea mali. E senya hyperglycemia e amanang le lijo (bakeng sa lihora tse 24 kamora tsamaiso ea insulin (feela) ha ho hlokahala e le secretion ea glucial.
E loketse bakuli bao tsoekere ea bona ea tsoekere e ntseng e laoloa hampe kamora tekanyetso e phahameng haholo ea metformin kapa sulfonylien a le mong. E sebelisoa hammoho le metsformin kapa sulfonylien.
E sebetsa ka mokhoa o its'etseng ka bokhutšoanyane, o bolelang hore o hlohlelletsa ho tsitsa ho insolin feela ha maemo a glucose a phahamela a le holimo ho a tloaelehileng, a thibelang "oversoot". Ka lebaka leo, e bonts'a kotsi e sa tsotelleng ea hypoglycemia.
E na le monyetla oa ho thibela tšoarelo le ho tsosa lisele tsa beta (tse bonoang lithutong tsa liphoofolo).
E fokotse takatso ea lijo 'me e sitisa ho rua molemo ha mmele, joalo ka ha ho bontšitsoe ka hlooho ea Golfiride.
PUSELETSO EA MAHALA
Liraglide ke GLP-1 Analog e nang le dalogy ea 97% ho glp - 1, e ka tlamang ho kenya glp-1 seceptor. Sengoli sa GLP-1 ke eona sepheo sa Native Glp-1, hormone ea insorein e khothalletsang secrein ea Glucose e itšetlehileng ka eona ho lisele tsa patsi. Ho fapana le GLP ea matsoalloa - 1, pharmacokineetic le pharmaCydynamic profiles ba Liraglide Kamora ho ikoalla ka tlas'a chelete, ketso ea eona ea ketso ea eona e telele e kenyeletsa: ingolehang ea ho kena-kenana le ho monya; ho tlama albin; Ho tsitsa enzyme ho phahameng le ka hona ho ne ho sa natse halofo ea bophelo.
Ts'ebetso ea Liraglide e kopantsoe ke tšebelisano ea eona e ikhethang le GLP-1 Recorce, e bakang keketseho ea Cyclichaste (kampong). Liraglide o ile a tsosa secreil secrein ka tsela e tšepahalang ea Glucose e tšepahalang, ha a fokotsa secretion e feteletseng ea Glucogon e itšetlehileng ka Glucose.
Ka hona, ha lekala la mali le hlaha, secreil secrein se susumetsoa, ha secretion ea gluagoon e thibetsoe. Ho fapana le hoo, Liraglide o fokotsa secrein secrein nakong ea hypoglycemia ntle le ho ama secretion ea gluagon. Mocha oa HYPPLECYSTIC oa Liragltoride o boetse o kenyelletsa nako e nyane ea nako ea ho tsosa ka mpeng. Liraglide e fokotsa boima ba 'mele le mafura a mafura a ho fokotsa tlala le matla a matla.