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Liraglutide Anti-Diabtisction bakeng sa Taolo ea Security ea Mali No.204656-20-2

Tlhaloso e khutšoane:

Motsoako o sebetsang:Liraglillede (Analog ea Bilicagoon - Joaloka Petide-1 (GLP-1) e hlahisoang ke tomoso ka theknoloji ea liphatsa tsa lefutso).

Lebitso la lik'hemik'hale:Arg34lys26- (N-c- (Γ-Glu (γ-Hexadecanoyl)) - GLP-1 [7-37]

Metsoako e meng:Distiri "hydrogen fysphate"


Lintlha tsa sehlahisoa

Li-tag tsa lihlahisoa

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Cas 204656-20-20-2 Foromo ea limolecular C172H265N43O51
Boima ba Molecular 3751.20 Ponahalo Tšoeu
Boemo ba polokelo Khanyetso e Khanyang, Ratey Degree Package Aluminium Fil Bag / Vial
Bohloeki ≥98% TS'ELISO Ketane e batang le phaello e pholileng

Metsoako ea Liraglide

Liraglturide

Motsoako o sebetsang:

Liraglillede (Analog ea Bilicagoon - Joaloka Petide-1 (GLP-1) e hlahisoang ke tomoso ka theknoloji ea liphatsa tsa lefutso).

Lebitso la lik'hemik'hale:

Arg34lys26- (N-c- (Γ-Glu (γ-Hexadecanoyl)) - GLP-1 [7-37]

Metsoako e meng:

Distiri "hydrogen fysphate"

Kopo

Mofuta oa 2 oa lefu la tsoekere

Liragllide e ntlafatsa taolo ea tsoekere ea mali. E senya hyperglycemia e amanang le lijo (bakeng sa lihora tse 24 kamora tsamaiso ea insulin (feela) ha ho hlokahala e le secretion ea glucial.
E loketse bakuli bao tsoekere ea bona ea tsoekere e ntseng e laoloa hampe kamora tekanyetso e phahameng haholo ea metformin kapa sulfonylien a le mong. E sebelisoa hammoho le metsformin kapa sulfonylien.
E sebetsa ka mokhoa o its'etseng ka bokhutšoanyane, o bolelang hore o hlohlelletsa ho tsitsa ho insolin feela ha maemo a glucose a phahamela a le holimo ho a tloaelehileng, a thibelang "oversoot". Ka lebaka leo, e bonts'a kotsi e sa tsotelleng ea hypoglycemia.
E na le monyetla oa ho thibela tšoarelo le ho tsosa lisele tsa beta (tse bonoang lithutong tsa liphoofolo).
E fokotse takatso ea lijo 'me e sitisa ho rua molemo ha mmele, joalo ka ha ho bontšitsoe ka hlooho ea Golfiride.

PUSELETSO EA MAHALA

Liraglide ke GLP-1 Analog e nang le dalogy ea 97% ho glp - 1, e ka tlamang ho kenya glp-1 seceptor. Sengoli sa GLP-1 ke eona sepheo sa Native Glp-1, hormone ea insorein e khothalletsang secrein ea Glucose e itšetlehileng ka eona ho lisele tsa patsi. Ho fapana le GLP ea matsoalloa - 1, pharmacokineetic le pharmaCydynamic profiles ba Liraglide Kamora ho ikoalla ka tlas'a chelete, ketso ea eona ea ketso ea eona e telele e kenyeletsa: ingolehang ea ho kena-kenana le ho monya; ho tlama albin; Ho tsitsa enzyme ho phahameng le ka hona ho ne ho sa natse halofo ea bophelo.

Ts'ebetso ea Liraglide e kopantsoe ke tšebelisano ea eona e ikhethang le GLP-1 Recorce, e bakang keketseho ea Cyclichaste (kampong). Liraglide o ile a tsosa secreil secrein ka tsela e tšepahalang ea Glucose e tšepahalang, ha a fokotsa secretion e feteletseng ea Glucogon e itšetlehileng ka Glucose.

Ka hona, ha lekala la mali le hlaha, secreil secrein se susumetsoa, ​​ha secretion ea gluagoon e thibetsoe. Ho fapana le hoo, Liraglide o fokotsa secrein secrein nakong ea hypoglycemia ntle le ho ama secretion ea gluagon. Mocha oa HYPPLECYSTIC oa Liragltoride o boetse o kenyelletsa nako e nyane ea nako ea ho tsosa ka mpeng. Liraglide e fokotsa boima ba 'mele le mafura a mafura a ho fokotsa tlala le matla a matla.


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