Eptifibatide bakeng sa Phekolo ea Acute Coronary Syndrome 188627-80-7
Lintlha tsa Sehlahisoa
| Lebitso | Eptifibatide |
| Nomoro ea CAS | 188627-80-7 |
| Mokhoa oa limolek'hule | Setšoantšo sa C35H49N11O9S2 |
| Boima ba molek'hule | 831.96 |
| Nomoro ea EINECS | 641-366-7 |
| Botenya | 1.60±0.1 g/cm3(E boletsoeng esale pele) |
| Maemo a polokelo | E koetsoe ka sehatsetsing, ka tlas'a -15 ° C |
Litlhaloso tse tšoanang
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6-(Aminoimi nomethyl) -N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteineamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDEBRIDGE,MPA1-CYS6).
Mohanyetsi oa Platelet Glycoprotein
Etifibatide (integrilin) ke mofuta o mocha oa polypeptide platelet glycoprotein IIb/IIIa receptor antagonist, e thibelang ho bokellana ha platelet le thrombosis ka ho thibela tsela ea ho qetela e tloaelehileng ea ho bokellana ha platelet. Ha e bapisoa le monoclonal antibody abciximab, eptifibatide e na le matla a matla, a tobileng le a tobileng a tlamang GPIIb/IIIa ka lebaka la ho ba teng ha sebaka se le seng sa amino acid - lysine ho nkela arginine sebaka. Ka hona, e lokela ho ba le phello e ntle ea phekolo kalafong ea ho kenella ea lefu le matla la coronary. Platelet glycoprotein IIb/IIIa receptor antagonist lithethefatsi li entsoe haholo, 'me hajoale ho na le mefuta e 3 ea litokisetso tse ka sebelisoang litsing tsa bongaka tsa machaba, abciximab, eptifibatide le tirofiban. ). Ho na le phihlelo e fokolang ea tšebeliso ea li-platelet glycoprotein GPIIb/IIIa li-receptor antagonists Chaena, 'me lithethefatsi tse teng le tsona li fokotsehile haholo. Ke sethethefatsi se le seng feela, tirofiban hydrochloride, se teng 'marakeng. Ka hona, ho ile ha etsoa platelet glycoprotein IIb e ncha. /IIIa bahanyetsi ba li-receptor ba bohlokoa. Domestic eptifibatide ke sehlahisoa sa ho etsisa se hlahisoang ke Chengdu Sino Biological Products Co., Ltd.
Karolelano
Classification of Antiplatelet Aggregation Drugs
Lithethefatsi tsa ho kopanya li-antiplatelet li ka aroloa ka likarolo tse tharo: 1. Cyclooxygenase-1 (COX-1) inhibitors, tse kang aspirin. 2. Thibela platelet aggregation e bakoang ke adenosine diphosphate (ADP), joalo ka clopidogrel, prasugrel, cangrelor, ticagrelor, joalo-joalo 3. Platelet glycoprotein Ⅱb / Ⅲa receptor antagonists, tse kang abciximab, eptifibatide, joalo-joalo EP3 glaban, prostafi receptor. li-inhibitors, likarolo tsa lik'hemik'hale tse sa tsoa etsoa le li-extracts tse sebetsang tse tsoang meriana ea setso ea Sechaena.
