Vancomycin ke lithibela-mafu tsa glycopeptide tse sebelisoang bakeng sa antibacterial
Lintlha tsa Sehlahisoa
| Lebitso | Vancomycin |
| Nomoro ea CAS | 1404-90-6 |
| Mokhoa oa limolek'hule | C66H75Cl2N9O24 |
| Boima ba molek'hule | 1449.25 |
| Nomoro ea EINECS | 215-772-6 |
| Botenya | 1.2882 (khakanyo e fosahetseng) |
| Lenane la refractive | 1.7350 (khakanyo) |
| Maemo a polokelo | E koaletsoe sebakeng se omileng, 2-8 ° C |
Litlhaloso tse tšoanang
Vancomycin(base le/orunSpecifiedsalts);VANCOMYCIN;VancomycinBase;(3S,6R,7R,22R,23S,26S,36R,38aR) -3-(2-Amino-2-oxoethyl) -44-[[2-O-(3-amino-2,) 3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy] -10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-7a-7 ,22,28,30,32-pentahydroxy-6-[[(2R)-4-methChemicalbookyl-2-(methylamino)-1-oxopentyl]amino] -2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23, 36-(iminomethano) -13,16:31,35-dimetheno-1H, 16H- [1,6,9] oxadiazacyclohexadecino [4,5-m] [10,2,16] benzoxadiazacyclotetracosine-26-carboxylicacid.
Tlhaloso
Vancomycin ke lithibela-mafu tsa glycopeptide. Mokhoa oa eona oa ts'ebetso ke ho tlama ka kamano e phahameng le alanylalanine pheletsong ea poly-terminal ea precursor peptide ea lebota la sele ea baktheria, e thibelang motsoako oa macromolecular peptidoglycan e etsang lebota la baktheria, e leng se fellang ka Ho timetsoa ha lerako la sele ho bolaea libaktheria. Vancomycin e sebetsa hantle bakeng sa mafu a tebileng a bakoang ke baktheria ea Gram-positive, haholo-holo e bakoang ke Staphylococcus aureus e hanyetsanang le methicillin, Staphylococcus epidermidis, le Enterococcus e hanyetsanang le lithibela-mafu tse ling kapa e sa sebetseng hantle.
Lipontšo
E lekanyelitsoe ho mafu a tsamaiso a bakoang ke Staphylococcus aureus (MRSA) e hanyetsanang le methicillin (MRSA) le mafu a mala le mafu a tsamaiso a bakoang ke Clostridium difficile; Bakuli ba penicillin-allergic ba ke ke ba sebelisa penicillin kapa cephalosporins ho bakuli ba nang le tšoaetso e matla ea staphylococcal, kapa ba nang le tšoaetso e matla ea staphylococcal ba hlōlehileng ho arabela lithibela-mafu tse ka holimo, vancomycin e ka sebelisoa. Sehlahisoa sena se boetse se sebelisoa bakeng sa phekolo ea Enterococcus endocarditis le Corynebacterium (Diphtheria-like) endocarditis ho batho ba sa lumellaneng le penicillin. Kalafo ea staphylococcus-induced arteriovenous shunt infections ho bakuli ba hemodialysis ba kulisoang ke penicillin le bao e seng ba allergic ho penicillin.
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