Pulegone
Pulegone API
Pulegone (molek'hule formula: C₁₀H₁₆O) ke monoterpene ketone motsoako o tsoang ho limela tsa tlhaho oli ea bohlokoa, e fumanoang haholo ka koena (Mentha), verbena (Verbena) le limela tse amanang le tsona. E le motsoako oa tlhaho o nang le monko o monate le ts'ebetso e phahameng ea likokoana-hloko, Pulegone e fumane tlhokomelo e kholo lefapheng la meriana ea tlhaho, chefo e bolaeang likokoanyana, lik'hemik'hale tse sebetsang tsa letsatsi le letsatsi le lisebelisoa tse tala tsa meriana lilemong tsa morao tjena.
Pulegone API eo re fanang ka eona ke motsoako oa bohloeki bo phahameng o fumanoang ka mokhoa o atlehang oa karohano le tlhoekiso, o finyellang litekanyetso tsa boleng ba litekanyetso tsa meriana kapa tsa indasteri 'me o loketse mefuta e sa tšoaneng ea tšebeliso e kang lipatlisiso tsa saense le nts'etsopele le motsoako oa bohareng.
Semelo sa lipatlisiso le litlamorao tsa pharmacological
1. Phello e khahlanong le ho ruruha
Palo e kholo ea lithuto tsa liteko tsa liphoofolo le lisele li fumane hore Pulegone e ka thibela ho lokolloa ha lintho tse thibelang ho ruruha (tse kang TNF-α, IL-1β le IL-6), ho laola litsela tsa lipontšo tsa COX-2 le NF-κB, 'me kahoo li bontša matla a mangata a khahlanong le ho ruruha mefuteng ea mafu a kang ramatiki ea ramatiki le ho ruruha ha letlalo.
2. Litlamorao tsa analgesic le sedative
Pulegone e na le phello e itseng ea thibelo tsamaisong ea methapo e bohareng 'me e bontša phello e hlakileng ea analgesic mefuteng ea liphoofolo. Mokhoa oa eona o ka 'na oa amana le taolo ea tsamaiso ea GABA neurotransmitter. E na le monyetla oa ho sebelisoa e le kalafo ea adjuvant bakeng sa matšoenyeho a fokolang kapa bohloko ba neuropathic.
3. Mosebetsi oa antibacterial le antifungal
Pulegone e na le liphello tse thibelang likokoana-hloko tse sa tšoaneng tsa Gram-positive le Gram-negative, tse kang Staphylococcus aureus, Escherichia coli, Bacillus subtilis, joalo-joalo; e boetse e bontša bokhoni ba ho thibela li-fungus tse kang Candida albicans le Aspergillus, 'me e loketse bakeng sa nts'etsopele ea li-preservatives tsa tlhaho le lihlahisoa tse thibelang tšoaetso tse thehiloeng limela.
4. Mosebetsi oa ho leleka likokoanyana le likokoanyana
Ka lebaka la phello ea eona e thibelang tsamaiso ea methapo ea kutlo, Pulegone e sebelisoa haholo linthong tsa tlhaho tse lelekang likokoanyana, tse khonang ho leleka menoang, likokoanyana, lintsintsi tsa litholoana, joalo-joalo, 'me li na le kamano e ntle ea tikoloho le ho senyeha ha tlhaho.
5. Ts'ebetso e ka 'nang ea e-ba khahlanong le hlahala (lipatlisiso tsa pele)
Liphuputso tsa pele li bontšitse hore Pulegone e ka 'na ea e-ba le phello e thibelang lisele tse ling tsa hlahala (joaloka lisele tsa kankere ea matsoele) ka ho etsa hore apoptosis e be teng, ho laola khatello ea kelello ea oxidative le mosebetsi oa mitochondrial, joalo-joalo, e fanang ka motheo oa lipatlisiso tsa metsoako ea tlhaho e khahlanong le mofetše.
Libaka tsa kopo le litlamorao tse lebelletsoeng
●Indasteri ea meriana
Joaloka molek'hule ea tlhaho ea tlhaho ho nts'etsopele ea lithethefatsi, Pulegone e ka sebelisoa e le setsi sa ho kenya letsoho ho kopanngoeng ha menthol (Menthol), menthone, li-additives tsa tatso le lithethefatsi tse ncha tse ka 'nang tsa e-ba khahlanong le ho ruruha le antibacterial. E na le litebello tse pharaletseng tsa ts'ebeliso ea ntlafatso ea meriana ea setso ea Machaena le litokisetso tsa meriana ea tlhaho.
●Litlolo le lik'hemik'hale tsa letsatsi le letsatsi
Ka monko oa eona oa monko o monate le ho thibela likokoana-hloko, Pulegone e sebelisoa ho lokisa melomo ea tlhaho, ho hlatsoa melomo, ho hlatsoa ha likokoana-hloko, li-mite spray, lihlahisoa tse lelekang menoang, joalo-joalo, ho finyella tlhokahalo ea 'maraka ea lik'hemik'hale tsa letsatsi le letsatsi tse tala, tse fokolang, le tse sireletsehileng haholo.
●Temo le lintho tse lelekang likokoanyana tse thibelang tikoloho
Pulegone, joalo ka sebolaea-likokoanyana sa tlhaho, e sebelisoa ho etsa chefo e entsoeng ka limela e hlokehang bakeng sa temo ea tlhaho, ho fokotsa tšilafalo ea tikoloho, ho ntlafatsa boleng ba lijalo, le ho latela leano le tsitsitseng la ntlafatso ea temo.
Boitlamo ba boleng ba Gentolex Group
Pulegone API e fanoeng ke Sehlopha sa rona sa Gentolex e na le litiiso tse latelang tsa boleng:
Bohloeki bo phahameng: bohloeki ≥99%, bo loketseng bakeng sa tšebeliso ea meriana le e phahameng ea indasteri
E lumellana le litlhoko tsa tsamaiso ea boleng ba GMP le ISO
Fana ka litlaleho tse felletseng tsa tlhahlobo ea boleng (COA, ho kenyeletsoa tlhahlobo ea GC/HPLC, tšepe e boima, lihlapolli tse setseng, meeli ea likokoana-hloko)
Litlhaloso tse ikhethileng li ka fanoa ho latela litlhoko tsa bareki, ho tšehetsa phepelo ho tloha ho ligrama ho isa ho lik'hilograma
