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Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH

Tlhaloso e Khutšoanyane:

Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OHke tetrapeptide e sirelelitsoeng eo hangata e sebelisoang liphuputsong tsa peptide synthesis. Lihlopha tsa Boc (tert-butyloxycarbonyl) le tBu (tert-butyl) li sebetsa e le lihlopha tse sireletsang ho thibela maikutlo a mahlakoreng nakong ea kopano ea ketane ea peptide. Ho kenyelletsoa ha Aib (α-aminoisobutyric acid) ho thusa ho etsa hore ho be le mekhoa ea helical le ho eketsa botsitso ba peptide. Tatelano ena ea peptide e ithutoa bakeng sa bokhoni ba eona ba tlhahlobo ea conformational, ho mena ha peptide, le joalo ka moaho oa ho nts'etsapele li-peptide tsa bioactive ka botsitso le boits'oaro bo ntlafalitsoeng.


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OHke tetrapeptide e sirelelitsoeng eo hangata e sebelisoang liphuputsong tsa peptide synthesis. Lihlopha tsa Boc (tert-butyloxycarbonyl) le tBu (tert-butyl) li sebetsa e le lihlopha tse sireletsang ho thibela maikutlo a mahlakoreng nakong ea kopano ea ketane ea peptide. Ho kenyelletsoa ha Aib (α-aminoisobutyric acid) ho thusa ho etsa hore ho be le mekhoa ea helical le ho eketsa botsitso ba peptide. Tatelano ena ea peptide e ithutoa bakeng sa bokhoni ba eona ba tlhahlobo ea conformational, ho mena ha peptide, le joalo ka moaho oa ho nts'etsapele li-peptide tsa bioactive ka botsitso le boits'oaro bo ntlafalitsoeng.


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