Tirzepatide Lyophilized High Purity 99% Peptide Powder 60mg ka vial bakeng sa lefu la tsoekere le tahlehelo ea boima ba 'mele.

Tirzepatide Lyophilized Powder (60 mg)

Tirzepatide (LY3298176) ke agonist ea pele e sebetsang ka bobeli e lebisang li-receptor tsa GIP (glucose-based insulinotropic polypeptide) le GLP-1 (glucagon-like peptide-1). E amohetse tumello ea US FDA ka Mots'eanong 2022 bakeng sa kalafo ea mofuta oa 2 lefu la tsoekere mellitus (T2DM) joalo ka tlatsetso ea lijo le boikoetliso.
Sehlahisoa sena se fanoa e le phofo ea 60mg lyophilized (e omisitsoeng ka leqhoa) ka har'a linkho, e lokelang ho tsosolosoa ka metsi a bacteriostatic pele ho tsamaiso. Ha e bapisoa le li-agonists tse le 'ngoe tsa GLP-1 tse kang semaglutide kapa dulaglutide, tirzepatide e bonts'a katleho e phahameng ea ho ntlafatsa taolo ea tsoekere ea mali, ho matlafatsa kutloisiso ea insulin, le ho tšehetsa tahlehelo e kholo ea boima ba' mele. Melemo ena e hlahisoa ke ts'ebetso ea eona ea li-dual-receptor synergistic ea ketso.

Melemo ea Bohlokoa
Taolo ea Glycemic

• E susumetsa tlhahiso ea insulin ka mokhoa o itšetlehileng ka tsoekere
• E fokotsa tlhahiso ea glucagon, e fokotsang boemo ba tsoekere maling
• E etsisa litlamorao tse kopaneng tsa metabolic tsa GIP le GLP-1

Boima ba Boima

• E khothalletsa ho khora le ho fokotsa ho ja caloric
• E bonts'itse tahlehelo e kholo le e tsitsitseng ea boima ba 'mele lithutong tsa bongaka

Bophelo bo botle ba pelo

• Lintlha tsa pele li bonts'a phokotso ea kotsi ea pelo ho bakuli ba nang le T2DM

Tšebeliso le Tekanyetso

• Tirzepatide lyophilized phofo (60 mg) e lokela ho tsosolosoa ka metsi a bacteriostatic pele e sebelisoa. Tsamaiso e etsoa ka ente ea subcutaneous, hangata hang ka beke ka letsatsi le le leng beke le beke.

Mofuta oa 2 oa lefu la tsoekere

• Ho qala lethal dose: 2.5 mg hang ka beke
• Titration: Eketsa libeke tse ling le tse ling tse 4 kamoo ho mamelletsoeng
• (→ 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg → 20 mg → 30 mg → 45 mg → ho fihla ho 60 mg)
• Tekanyetso e tloaelehileng: 10-30 mg beke le beke
• Boholo Tekanyetso: 60 mg beke le beke

Botenya / Boima ba Boima

• Ho qala lethal dose: 2.5 mg hang ka beke
• Titration: Butle-butle ho eketseha ha lethal dose joalokaha ho mamelloa
• (2.5 → 5 → 7.5 → 10 → 12.5 → 15 → 20 → 30 → 45 → 60 mg)
• Tekanyetso e tloaelehileng: 30-60 mg beke le beke
• Boholo Tekanyetso: 60 mg beke le beke

Khothalletsoang Tekanyo Papiso

Hlokomela:Etsa bonnete ba hore tekanyo e 'ngoe le e' ngoe e fetileng e mamelloa hantle pele e eketseha.

Liphello Tse ka Etsahalang Tse Ngata

• Gastrointestinal: Ho nyekeloa ke pelo, ho hlatsa, letšollo le ho se thabise ka mpeng (hangata nakong ea ho qala)
• Hypoglycemia: Ka kakaretso kotsi e tlase, empa e eketseha ha e kopantsoe le litlhare tse ling tsa antidiabetic
• Likarabo tsa Sebaka sa Ente: Bofubelu, ho hlohlona, ​​ho ruruha, kapa bohloko bo fokolang sebakeng seo
• Pancreatitis: e sa tloaelehang, empa e ka etsahala; hlokomela bakeng sa bohloko bo sa feleng ba ka mpeng
• Liphello Tsa Renal: Ho ka 'na ha hlokahala hore batho ba itseng ba hlahlobe tšebetso ea liphio

Pharmacokinetics

• Halofo ea Bophelo: Hoo e ka bang beke e 1
• Hangata Dosing Frequency: E tšehetsa tsamaiso e bonolo hang ka beke

Kakaretso
Tirzepatide 60 mg lyophilized powder e emela tsoelo-pele ea phekolo ea moloko o latelang, e kopanyang taolo e matla ea glycemic le katleho e tsotehang ea ho lahleheloa ke boima ba 'mele le tšireletso e ka bang teng ea pelo.
Ka kemiso ea butle-butle ea titration (2.5 mg → ho fihlela ho 60 mg), e lumella ho mamella le ho feto-fetoha ha maemo bakeng sa phekolo ea motho ka mong. Tsamaiso ea eona hang ka beke e ntlafatsa ho latela melao, e e etsa khetho e ncha le e sebetsang bakeng sa taolo ea lefu la tsoekere la mofuta oa 2 le botenya maemong a tsoetseng pele a bongaka le lipatlisiso.