RU-58841 E Sebelisitsoe e le Thibelo ea ho lahleheloa ke Moriri le ho ba Lefatla la Banna
Lintlha tsa Sehlahisoa
| Lebitso | RU-58841 |
| Nomoro ea CAS | 154992-24-2 |
| Mokhoa oa limolek'hule | C17H18F3N3O3 |
| Boima ba molek'hule | 369.34 |
| Nomoro ea EINECS | 1592732-453-0 |
| Ntlha e belang | 493.6±55.0 °C(E boletsoeng esale pele) |
| Botenya | 1.39 |
| Boemo ba polokelo | E tiisitsoe ka sehatsetsing, ka tlas'a -20°C |
| Sebopeho | Phofo |
| Mmala | Bosoeu |
| Ho paka | PE mokotla + Aluminium mokotla |
Litlhaloso tse tšoanang
RU58841;4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile;4--[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazomethyl-flu-fluo] onnitrile;4-[3-(4-Hydroxybutyl) -4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl] -2-(trifluoroMethyl) ben zonitrile;RU-58841E:candyli(at)speedgainpharma(dot)com;CS-637;RU588841;RU58841;RU58841;RU-58841
Phello ea Pharmacological
Tlhaloso
RU 58841 (PSK-3841) ke mohanyetsi oa li-androgen receptor tse khothalletsang ho hōla ha moriri.RU58841 ke moriana oa lipatlisiso o entsoeng bakeng sa phekolo khahlanong le alopecia ea androgenic, e tsejoang hape e le lefatla la monna (MPD).
E le topical anti-androgen, molao-motheo oa eona oa ketso ha o tšoane le oa finasteride. Finasteride e sebetsa ka kotloloho ho 5α reductase, e thibela phetoho ea testosterone ho DHT, mme e fokotsa litaba tsa DHT 'meleng. RU58841 e thibela ho kopana pakeng tsa dihydrotestosterone le li-receptor tsa moriri oa moriri, ha e fokotse ka ho toba litaba tsa DHT, empa e fokotsa ho tlama ha DHT le li-receptor tsa moriri, e le ho finyella morero oa ho phekola alopecia ea androgenetic.
4- [3- (4-Hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2- (trifluoromethyl) benzonitrile e ka sebelisoa e le meriana Li-chemical synthesis intermediates.Haeba 4--[3- (4-hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2-(trifluoromethyl) benzonitrile e hema, Tsamaisetsa mokuli moeeng o hloekileng;Tabeng ea ho kopana le letlalo, tlosa liaparo tse silafetseng, hlatsoa letlalo ka botlalo ka sesepa le metsi, 'me u batle ngaka haeba u sa phutholoha;
Lehlakore la Phello
RU58841 e sebelisoa letlalong la hlooho, e kenngoa ke moriri oa moriri, 'me ka khopolo, e ka kena maling' me ea ama likarolo tse ling tsa 'mele. Empa ha ho litla-morao tsa systemic tse fumanoeng lithutong tsa ts'ebeliso ea lihlooho ho litšoene. Leha ho le joalo, batho ba bang ba lekileng RU58841 ba bolela hore ba bile le litla-morao tse ka 'nang tsa e-ba teng ka ho sebelisa RU, ho kenyelletsa ho halefa ha letlalo, ho fokotseha ha libido, ho se sebetse ha erectile, ho nyekeloa ke pelo, mahlo a khubelu, ho tsekela le hlooho.
