Lihlahisoa
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CJC-1295
CJC-1295 API e hlahisoa ho sebelisoa thekenoloji ea solid phase peptide synthesis (SPPS) mme e hloekisoa ka ho sebelisa HPLC ho fihlela bohloeki bo phahameng le ho lumellana ha batch-to-batch.
Likarolo tsa Sehlahisoa:Bohloeki ≥ 99%
Li-solvents tse setseng tse tlase le litšepe tse boima
Endotoxin-mahala, tsela e seng ea immunogenic synthesis
Lipalo tse u ka li khethang: mg ho isa ho lik'hilograma
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NAD+
Likarolo tsa API:
Bohloeki bo phahameng ≥99%
Pharmaceutical-grade NAD+
Litekanyetso tsa tlhahiso tse kang GMP
NAD+ API e loketse ho sebelisoa ho li-nutraceuticals, liente, le liphekolo tse tsoetseng pele tsa metabolic.
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Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OHke tetrapeptide e sirelelitsoeng eo hangata e sebelisoang liphuputsong tsa peptide synthesis. Lihlopha tsa Boc (tert-butyloxycarbonyl) le tBu (tert-butyl) li sebetsa e le lihlopha tse sireletsang ho thibela maikutlo a mahlakoreng nakong ea kopano ea ketane ea peptide. Ho kenyelletsoa ha Aib (α-aminoisobutyric acid) ho thusa ho etsa hore ho be le mekhoa ea helical le ho eketsa botsitso ba peptide. Tatelano ena ea peptide e ithutoa bakeng sa bokhoni ba eona ba tlhahlobo ea conformational, ho mena ha peptide, le joalo ka moaho oa ho nts'etsapele li-peptide tsa bioactive ka botsitso le boits'oaro bo ntlafalitsoeng.
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Cagrilintide
Cagrilintide ke amylin receptor agonist ea maiketsetso, ea nako e telele, e etselitsoeng ho phekola botenya le mathata a amanang le boima ba 'mele. Ka ho etsisa hormone ea tlhaho ea amylin, e thusa ho laola takatso ea lijo, ho lieha ho tsoa ka mpeng, le ho matlafatsa ho khora. API ea rona ea boleng bo phahameng ea Cagrilintide e hlahisoa ka lik'hemik'hale tsa lik'hemik'hale 'me e kopana le litekanyetso tsa litekanyetso tsa meriana, e leng se etsang hore e loketse ho sebelisoa mefuteng e tsoetseng pele ea ho laola boima ba' mele.
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Tesamorelin
Tesamorelin API e sebelisa theknoloji e tsoetseng pele ea "peptide synthesis" (SPPS) mme e na le lintlha tse latelang:
Bohloeki ≥99% (HPLC)
Ha ho na endotoxin, lirafshoa tse boima, li-solvents tse setseng tse lekiloeng
Tatelano ea amino acid le sebopeho se tiisitsoeng ke LC-MS/NMR
Fana ka tlhahiso e ikhethileng ka ligrama ho isa ho lik'hilograma -
Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH ke moaho oa dipeptide o sebelisoang ho solid-phase peptide synthesis (SPPS). E kopanya isoleucine e sirelelitsoeng ea Fmoc le Aib (α-aminoisobutyric acid), e seng ea tlhaho ea amino acid e matlafatsang botsitso ba helix le ho hanyetsa protease.
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![Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH](https://cdn.globalso.com/gentolexgroup/Glepaglutide6-300x300.png)
Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH ke mohaho o sebetsang oa amino acid o etselitsoeng ho fana ka lithethefatsi tse lebisitsoeng le bioconjugation. E na le karolo ea Eic (eicosanoid) bakeng sa tšebelisano ea lipid, γ-Glu bakeng sa ho shebisisa, le li-spacers tsa AEEA bakeng sa ho tenyetseha.
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Boc-Tyr(tBu)-Aib-OH
Boc-Tyr(tBu)-Aib-OH ke moaho oa dipeptide o sirelelitsoeng o sebelisoang ho kopantseng peptide synthesis, ho kopanya Boc-protected tyrosine le Aib (α-aminoisobutyric acid). Masala a Aib a matlafatsa sebopeho sa helix le ho hanyetsa protease.
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Boc-His(Trt)-Ala-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Ala-Glu(OtBu)-Gly-OH ke sekhechana se sirelelitsoeng sa tetrapeptide se sebelisoang ho solid-phase peptide synthesis (SPPS) le nts'etsopele ea lithethefatsi tsa peptide. E kenyelletsa lihlopha tse sireletsang bakeng sa orthogonal synthesis mme e fana ka tatellano e sebetsang molemong oa moralo oa peptide oa bioactive le oa sebopeho.
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Fmoc-Ls(Pal-Glu-OtBu)-OH
Fmoc-Ls(Pal-Glu-OtBu) -OH ke mohaho o khethehileng oa lipidated amino acid o etselitsoeng ho kopanya peptide-lipid. E na le lysine e sirelelitsoeng ke Fmoc e nang le ketane ea mahlakoreng ea palmitoyl-glutamate, e matlafatsang kamano ea lera le bioavailability.
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Fmoc-Hae-Aib-OH
Fmoc-His-Aib-OH ke letlapa la moaho la dipeptide le sebelisoang ho kopantseng peptide synthesis, ho kopanya Fmoc-protected histidine le Aib (α-aminoisobutyric acid). Aib e hlahisa conformational rigidity, e etsa hore e be ea bohlokoa bakeng sa ho rala li-peptide tsa helical le tse tsitsitseng.
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Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH ke sekhechana se sirelelitsoeng sa tetrapeptide se sebelisoang ho peptide synthesis le nts'etsopele ea lithethefatsi. E na le lihlopha tse sebetsang tse sirelelitsoeng ka mokhoa o hlophisitsoeng bakeng sa ho kopanya ka mehato le likarolo tsa Aib (α-aminoisobutyric acid) ho matlafatsa botsitso ba helix le conformational rigidity.