Orlistat 96829-588- e fokotsa ho monya mafura a tsoang Sitinery, ho lahleheloa ke boima ba 'mele
Lintlha tsa sehlahisoa
| Lebitso | Orlistat |
| Nomoro ea CAS | 96829-58-2 |
| Foromo ea limolecular | C29h53no5 |
| Boima ba Molecular | 495.73 |
| Nomoro ea Einecs | 639-755-1 |
| Ntlha ea ho qhibiliha | <50 ° C |
| Letsoalo | 0.976 ± 0.06G / cm3 (e boletsoeng esale pele) |
| Boemo ba polokelo | 2-8 ° C |
| Foromo | Phofo |
| Mmala | Tšoeu |
| Acidity cormety | (pka) 14.59 ± 0.23 (esale pele) |
Synonyms
(S)-myyylamino-methyl-pentanoicacid (2s, 3 - [[2s, 3s) -3-hext Ormyl-L-Leucne (1s) -1 - [[2) [32
Phello ea pharmaColoCologana
Thepa
Mohloa o mosoeu oa kristasine, hoo e batlang e sa khathatse ka metsing, e qhibiliha habonolo ho methanil le ho qhibiliha lintlha tsa pyrolyze, ho qhibiliha ho 40 ℃ ~ 42 42 ℃. Molek'hule ea eona ke Diastereomer e nang le litsi tse 'ne tsa li-chil tse' ne, kahara tharollo ea 529nm, tharollo ea eona ea Bota e na le sebaka se fosahetseng sa ho potoloha.
Mokhoa oa ketso
Orlistat ke Lipzit e ikhethileng le e matla ea pastroutination, e neng e ntse e sebetsa ka holimo e kaholimo ka ho theha kamano ea cevase ka mpeng le mala a manyane. Li-enzyme tse qaqileng li ke ke tsa roba mafura lijong ka acid acid ea acid le bukana ea li-glycerol tse ka kenang lipakeng tsa mafura le ho fokotsa boima ba mafura le ho fokotsa boima ba mafura. Ntle le moo, lithuto tse ling li fumane hore liphuputso tse ling li thibela ho kenella ha cholesterol ka li-prothein 1 (mongobo oa protheine ea 1 (Niemann-picc1).
Matšoao
Sehlahisoa sena se jang lijo tse bobebe tsa hypocaloric se bonolo se tšoantšetsa tšoaro ea nako e telele ea ho tšoasa le batho ba fetang boima ba kotsi e amanang le botenya. Sehlahisoa sena se na le taolo ea boima ba 'mele (tahlehelo ea boima ba' mele, ho lokisa boima ba 'mele le thibelo ea rebound). Ho nka li-orlistat li ka fokotsa maemo a kotsi a kotsi le mahlomola a maloetse a mang a hloekileng, ho kenyeletsoa lefu la tsoekere la tsoekere, hyperbinunemia, hypertinsulmamia, hypertination
Likhatiso tsa Bongaka
E ka fokotsa ho monya ka livithamini A, D le E. E ka tlatsetsoa ka sehlahisoa sena ka nako e le 'ngoe. Haeba u nka litokisetso tse nang le li-vithamine A, D le E (e joalo ka li-multivitamins), u lokela ho nka sehlahisoa sena lihora tse 2 kamora ho robala. Batho ba nang le lefu la tsoekere la 2 ba ka hloka ho fokotsa tekanyetso ea li-sypoglycemicms tsa molomo (mohlala, sulfonyllunas). Tsamaiso ea CO-Accolosporine e ka fella ka ho fokotseha ha plasma monko oa morao-rao. Ts'ebeliso ea nako ea li-amiodarone e ka baka ho monya letsoho la morao-rao le ho fokotsehile.
