Retatrutide: Naleli e Tsoang e ka Fetola Botenya le Phekolo ea Lefu la Lefu la tsoekere

Lilemong tsa morao tjena, ho phahama ha lithethefatsi tsa GLP-1 tse kang semaglutide le tirzepatide ho pakile hore ho theola boima ba 'mele hoa khoneha ntle le ho buuoa. Joale,Retatrutide, Motlatsi oa li-receptor tse tharo tse entsoeng ke Eli Lilly, o hohela tlhokomelo ea lefats'e ho tsoa ho sechaba sa bongaka le ba lichelete ka ho tšoana bakeng sa bokhoni ba eona ba ho fana ka liphello tse kholoanyane ka mokhoa o ikhethang oa ts'ebetso.

Mokhoa o Hlahisang Lipheo tse ngata

Retatrutide e ikhetha ka eonats'ebetso ea nako e le 'ngoe ea li-receptor tse tharo:

• GLP-1 receptor- E thibela takatso ea lijo, e liehisa ho tsoa ka mpeng, 'me e ntlafatsa tlhahiso ea insulin

• GIP receptor- E ntlafatsa ho lokolloa ha insulin hape e ntlafatsa metabolism ea tsoekere

• Glucagon receptor- E eketsa sekhahla sa metabolism ea basal, e khothalletsa ho senyeha ha mafura, 'me e matlafatsa tšebeliso ea matla

Mokhoa ona oa "liketso tse tharo" ha o tšehetse feela ho theola boima ba 'mele empa hape o ntlafatsa likarolo tse ngata tsa bophelo bo botle ba metabolism, ho kenyelletsa taolo ea tsoekere, profil ea lipid le phokotso ea mafura a sebete.

Liphetho tse Hlollang tsa Pele tsa Tleliniki

Litekong tsa pele tsa tleliniki, batho ba se nang lefu la tsoekere ba nang le botenya ba ileng ba nka Retatrutide bakeng sa libeke tse ka bang 48 ba bone.ho theola boima ba 'mele ho feta 20%, le barupeluoa ba bang ba fihletseng hoo e ka bang 24% -ba atamela katleho ea ho buuoa ka bariatric. Har'a batho ba nang le lefu la tsoekere la mofuta oa 2, moriana ha oa ka oa fokotsa maemo a HbA1c haholo empa hape o bonts'itse monyetla oa ho ntlafatsa maemo a kotsi a pelo le metabolic.

Menyetla le Mathata a ka Pele

Leha Retatrutide e bonts'a ts'episo e makatsang, e ntse e le litekong tsa kliniki tsa mohato oa 3 mme ha ho na monyetla oa ho fihla 'marakeng pele.2026–2027. Hore na e ka fetoha "mofetoleli oa lipapali" ho tla itšetleha ka:

1. Tšireletseho ea nako e telele- Ho beha leihlo litlamorao tse ncha kapa tse ntlafalitsoeng ha li bapisoa le litlhare tse teng tsa GLP-1

2. Ho mamella le ho khomarela- Ho etsa qeto ea hore na ts'ebetso e phahameng e tla ka litšenyehelo tsa litekanyetso tse phahameng tsa ho khaotsa

3. Boikemisetso ba khoebo- Theko, tšireletso ea inshorense, le phapang e hlakileng ho lihlahisoa tse hlolisang

Phello e ka bang teng ea 'Maraka

Haeba Retatrutide e ka ba le botsitso bo nepahetseng lipakeng tsa polokeho, ts'ebetso e sebetsang, le ho khoneha, e ka beha maemo a macha bakeng sa meriana ea ho theola boima ba 'mele le ho sutumelletsa botenya le kalafo ea lefu la tsoekere mehleng eaboitshunyako bo nepahetseng ba maikemisetso a mangata-mohlomong ho hlophisa bocha mmaraka oa lefats'e oa lefu la metabolic.