Lebitso | Ibutamoren misylate |
Nomoro ea CAS | 159752-10-0 |
Foromo ea limolecular | C28h4040404s2 |
Boima ba Molecular | 624.77 |
Nomoro ea Einecs | 1308068-626-2 |
Ntlha ea ho qhibiliha | 164-170 ° C |
Fulubility | H2O: Soluble5mg / ML, Hlakileng |
Boemo ba polokelo | 2-8 ° C |
Foromo | Phofo |
Mmala | Tšoeu ho beige |
Packing | Pla ea mokotla + aluminium Bag |
Mk-677; 2-amino-n - [1r) -2- [1,2-diydro-1- (Methylsulfonyl) Spiro [3H-Indole-3,4'-with irini] -1'-yl] -2-oxo-1 - [phenylmethoxy) Methyl] Ethyl ja; mk677 (ibutamorenmes); mk-677; mk0677; mk067; mk677; mk677; mk677; c S-1402; mk677kbkotamoren; mk677kbk67777777777717767k7
Tlhaloso
IBhenolen ke setlhare se etsang secretion se nang le tšusumetso, se susumetsang, se susumetsang ho tsosa li-hormone tse fapaneng.
Ts'ebetso
Mesyala e bontsitsoe ho eketsa tokollo le ho atafala le ho hlahisoa ha li-plasma tse ntseng li tsoela pele ho eketsa li-plasma tsa li-hormone tse ling ho kenyelletsa le maemo a Ch le Insul. Phekolo e ka Khoalang Ntle le Nts'etsopele ea Tsoelo-pele ea Lihote tsa Hormone, joalo ka bana kapa lithuto tsa batho tse tsofetseng, tse e etsang kalafo e tšekaletseng bakeng sa batho ba baholo ba tsofetseng. E boetse e fetola metabolism ea mafura a mafura, kahoo e kanna ea ba le lits'ebetso tsa tlhekefello ea botenya.
Lithutong tsa vivo
Ibutamoren Mesylate (5 MG / KG / Day Ibutamoren Mesylays ho etsa liphetho ho sena keketseho e kholo ea CSF igf-1 kapa ea Gh ka matsatsi a 7 kapa 15 ea thuto. Ho tobetsa litoeba ka gh ho thibela ts'ebetso ea li-neuurons tsena ka ibutamoren misylate (50 μg, IP). Ka har'a litoeba tsa ho kokota, matla ka bobeli le octreotorode ha a na ho thibela ho thibela ho eketsa li-neuns tsa arcute neuurons. Tsamaiso ea OLL ea OLS ea MK-0677 e amana le keketseho ea bohlokoa ho GH le IGF-Istelo maemo a bolokiloeng bakeng sa kalafo. Tsamaiso ea GH ea GH e latelang Mk-0677 Tsamaiso e na le evadic e eketseha ka holimo ho taolo. MK-0677 Haholo ke ho eketsa haholo hoaba ea leqheka ka mor'a tsamaiso ea molomo. MK-0677 ke karolo e matla ea lehloa e susumetsang keketseho e kholo, e telele e tšoarellang ea GH ha e tsamaisoa ka molomo kapa iv