Gnrh Antgonist e sebelisitsoeng bakeng sa Pepside Synthesis
Lintlha tsa sehlahisoa
| NO | Lihlahisoa | Cas No. | Kopo | Letšoao la boleng ba boleng | ||||
| Bohloeki | Isomer | Pholoso e ikhethileng | * Max1 | Mongobo | ||||
| 1 | Fmoc-3- (2-naphthyl) -d-ala-oh | 138774-94-4 | Lihlahisoa tse ngata | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 2 | Ac-3- (2-naphthyl) -d-ala-oh | 37440-01-0 | Lihlahisoa tse ngata | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 3 | Fmoc-3- (3-pyrininyl) -d-ala-oh | 142994-45-4 | Lihlahisoa tse ngata | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 4 | Fmoc-4-chloro-d-Phe -h-oh | 142994-19-2 | Lihlahisoa tse ngata | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 5 | Fmoc-d-cit-oh | 200344-33-8 | Cetrorelix | ≥99.5% | ≤0.1% | ≤0.1% | ≤0.2% | ≤1.0% |
| 6 | Fmoc-d-ah.h2o | 79990-15-1 | Lihlahisoa tse ngata | ≥99.5% | ≤0.1% | ≤0.1% | ≤0.2% | ≤6.5% |
| 7 | Fmoc-d-aph (tbucbm) -oh | 143397555-21-3 | Khafetsa | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 8 | Fmoc-d-aph (cbm) -oh | 324017-22-3 | Khafetsa | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 9 | Fmoc-l-aph (l-hor)- | 1253282--3 | Khafetsa | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 10 | Fmoc-l-lys (ir, boc) -oh | 201003-48-7 | Khafetsa | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 11 | Fmoc-n-me-me-my (tvr (tkhu) -oh | 133373-24-7 | Abelalix | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 12 | Fmoc-d-ann (trt) -oh | 180570-71-2 | Abelalix | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 13 | Fmoc-homoarg (et) 2-oh.hcl | 1864003-26-8 | Ganirelix | ≥95.0% | ≤0.5% | ≤1.0% | ≤2.0% | ≤2.0% |
| 14 | Fmoc-d-homoarg (et) 2-oh.hcl | 2098497-24-4 | Ganirelix | ≥95.0% | ≤0.5% | ≤1.0% | ≤2.0% | ≤2.0% |
| 15 | Fmoc-Lys (Niotinoyl) -oh | 252049-11-9 | Antide | ≥98.0% | ≤0.2% | ≤0.3% | ≤0.5% | ≤1.0% |
| 16 | Fmoc-D-Lys (Nikotinoyl) -oh | 252049-12-0 | Antide | ≥98.0% | ≤0.2% | ≤0.3% | ≤0.5% | ≤1.0% |
* Max1 = ho hlaka ho sa tsejoeng
Letšoao le leng:
- acid acid: ≤0.02% (lihlahisoa tsohle)
- Ethyl acetate: ≤0.5% (lihlahisoa tsohle)
- Joala: ≤0.5% (lihlahisoa tsohle)
Toc le boits'oaro
Toc le boitšoaro ba phepelo ea mantlha le lintlha tsa ho khutla li hlokofalitsoe nako le nako. Toc e shebelletsoe ka QC ka beke e 'ngoe le e' ngoe. Ho ba le boitšoaro bo hitsoeng shebene ka marang-rang 'me ho tlalehiloe ka ho hloekisoa ha seteishene sa metsi sa metsi hanngoe ka lihora tse' ne. Moetlo o beiloe leihlo ho The Ro, Bopharamo Botsa le Seteishene sa ho khutla ka botlalo. Tsela ea metsi a hloekisitsoeng e sebakeng se hloekisitsoeng le e tiisa litlhaloso tsa pele ho 1.3 μs / usp). Bakeng sa phepelo ea mantlha le ho khutlisa lintlha, liteko tse felletseng. e etsoa beke e 'ngoe le e' ngoe, hobane e 'ngoe ea ho sebelisa seqhomane se potolohileng, ho etsoa tlhahlobo e felletseng hang ka khoeli. Teko e felletseng e kenyelletsa litlhaku, PH, Nitte, Ammonia, Moeti oa Ammonia, oa Amonia, Litols tse boima, meeli e boima, litsietsi tsa likokoana-hloko.
