Glucagon

Glucagon API

Glucagon ke hormone ea tlhaho ea peptide e sebelisoang e le kalafo ea tšohanyetso bakeng sa hypoglycemia e matla mme e ithutoa ka karolo ea eona taolong ea metabolic, ho theola boima ba 'mele le tlhahlobo ea tšilo ea lijo.

Mokhoa le Lipatlisiso:

Glucagon e tlama ho glucagon receptor (GCGR) e sebeteng, e susumetsang:

Ho senyeha ha glycogen ho eketsa tsoekere ea mali

Lipolysis le ho bokella matla

Ho feto-fetoha ha motility ka gastrointestinal (e sebelisoang ho radiology)

E ntse e hlahlojoa hape ka botenya, lefu la tsoekere la mofuta oa 2, le liphekolo tse peli / tse tharo tsa agonist tse nang le GLP-1 le GIP.

Likarolo tsa API (Gentolex Group):

Peptide ea boleng bo holimo (≥99%)

E hlahisoa ka solid-phase peptide synthesis (SPPS)

Boleng bo kang ba GMP

E loketse li-injection le lisebelisoa tsa tšohanyetso

Glucagon API e bohlokoa bakeng sa pholoso ea hypoglycemia, litšoantšo tsa tlhahlobo, le lipatlisiso tsa bothata ba metabolic.