GLP-1 E Sirelelitsoeng Amino Acid bakeng sa Phetoho ea Side Chain
Lintlha tsa Sehlahisoa
| NO. | Lihlahisoa | Nomoro ea CAS. | Kopo | Sesupo sa Boleng ba Bohlokoa | ||||
| Bohloeki | Isomer | SI * | Max* | Mongobo | ||||
| 1 | Fmoc-Ls(Mtt)-OH | 167393-62-6 | Lysine lehlakoreng ketane phetolo | ≥99.0% | ≤0.1% | ≤0.2% | ≤0.3% | ≤1.0% |
| 2 | Fmoc-Ls(Alloc)-OH | 146982-27-6 | Lysine lehlakoreng ketane phetolo | ≥99.5% | ≤0.1% | ≤0.1% | ≤0.2% | ≤1.0% |
| 3 | Fmoc-Ls(ivDde)-OH | 150629-67-7 | Lysine lehlakoreng ketane phetolo | ≥98.0% | ≤0.2% | ≤0.3% | ≤0.5% | ≤1.0% |
| 4 | Fmoc-Ls(Mmt)-OH | 159857-60-0 | Lysine lehlakoreng ketane phetolo | ≥98.0% | ≤0.2% | ≤0.3% | ≤0.5% | ≤1.0% |
| 5 | Fmoc-Glu-OtBu | 84793-07-7 | LiraglutideSemaglutide | ≥99.5% | ≤0.1% | ≤0.1% | ≤0.2% | ≤1.0% |
| 6 | Glu-OtBu | 45120-30-7 | LiraglutideSemaglutide | ≥99.5% | ≤0.1% | ≤0.1% | ≤0.2% | ≤1.0% |
| 7 | Octadecanedioic acid | 871-70-5 | Semaglutide | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 8 | Octadecanedioic acid mono-tert-butyl ester | 843666-40-0 | Semaglutide | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 9 | tBu-OOC-C16-CO-Glu-OtBu | 1188328-39-3 | SemaglutideSekhechana sa A | ≥98.0% | ≤0.2% | ≤0.5% | ≤0.5% | ≤1.0% |
| 10 | AEEA | 134978-97-5 | SemaglutideAlbuvirtide | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 11 | AEEA-OH.HCl | 134979-01-4 | SemaglutideAlbuvirtide | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 12 | Fmoc-AEEA-OH | 166108-71-0 | SemaglutideAlbuvirtide | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 13 | Boc-AEEA-OH | 108466-89-3 | Semaglutide | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 14 | AEEA-AEEA | 1143516-05-5 | Semaglutide | ≥98.0% | ≤0.2% | ≤0.5% | ≤0.5% | ≤1.0% |
| 15 | Fmoc-AEEA-AEEA-OH | 560088-89-3 | SemaglutideKarolo ea B | ≥98.0% | ≤0.2% | ≤0.5% | ≤0.5% | ≤1.0% |
| 16 | Octa(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH | 1118767-16-0 | SemaglutideKarolo ea C | ≥98.0% | ≤0.2% | ≤0.5% | ≤0.5% | ≤1.0% |
| 17 | tBu-OOC-C16-CO-Glu(AEEA-AEEA-NHS)-OtBu | 1118767-15-9 | SemaglutideKarolo ea D | ≥96.0% | ≤0.5% | ≤1.0% | ≤1.0% | ≤1.0% |
| 18 | Fmoc-Ls(tBu-OOC-C16-CO-Glu(AEEA-AEEA)-OtBu)-OH | 1662688-20-1 | Semaglutide Fragment E | ≥96.0% | ≤0.5% | ≤1.0% | ≤1.0% | ≤1.0% |
| 19 | Boc-His(Trt)-OH | 32926-43-5 | Qetellong ke histidine | ≥99.5% | ≤0.1% | ≤0.1% | ≤0.2% | ≤4.0% |
| 20 | Fmoc-Aib-OH | 94744-50-0 | Semaglutide | ≥99.5% | / | ≤0.1% | ≤0.2% | ≤1.0% |
| 21 | Boc-His(Trt)-Aib-OH | 2061897-68-3 | Semaglutide | ≥99.0% | ≤0.1% | ≤0.2% | ≤0.3% | ≤2.0% |
| 22 | Fmoc-Glu(OtBu)-Gly-OH | 866044-63-5 | Analogue ea GLP-1 | ≥99.5% | ≤0.1% | ≤0.2% | ≤0.2% | ≤1.0% |
| 23 | Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH | 1169630-31-2? | Semaglutide Fragment F | ≥98.0% | ≤0.2% | ≤0.5% | ≤0.5% | ≤1.0% |
| 24 | Boc-His(Trt)-Aib-Glu(OtBu)-Gly-NHS | 1169630-40-3 | Semaglutide Fragment G | ≥96.0% | ≤0.5% | ≤1.0% | ≤1.0% | ≤1.0% |
| 25 | Fmoc-Arg(pbf)-Gly-OH | 660846-80-0 | Analogue ea GLP-1 | ≥99.5% | ≤0.1% | ≤0.2% | ≤0.2% | ≤1.0% |
| 26 | Fmoc-Ala-Ala-OH | 87512-31-0 | Analogue ea GLP-1 | ≥99.5% | ≤0.1% | ≤0.2% | ≤0.2% | ≤1.0% |
| 27 | Fmoc-Thr(tBu)-Phe-OH | 1260609-75-3 ? | Analogue ea GLP-1 | ≥99.5% | ≤0.1% | ≤0.2% | ≤0.2% | ≤1.0% |
| 28 | Asiti ea Palmitic | 1957/10/3 | Karolo ea 1 ea Liraglutide | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 29 | Palm-Glu-OtBu | NA | Karolo ea 2 ea Liraglutide | ≥98.0% | ≤0.2% | ≤0.5% | ≤0.5% | ≤1.0% |
| 30 | Palm-Glu(NES)-OtBu | NA | Karolo ea 3 ea Liraglutide | ≥96.0% | ≤0.5% | ≤1.0% | ≤1.0% | ≤1.0% |
| 31 | Fmoc-Ls(Palm-Glu-OtBu)-OH | 1491158-62-3 | Liraglutide | ≥98.0% | ≤0.2% | ≤0.5% | ≤0.5% | ≤1.0% |
| 32 | Hexadecanedioic acid | 505-54-4 | Insulin degludec | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 33 | Hexadecanedioic acid mono-tert-butyl ester | 843666-27-3 | Insulin degludec | ≥99.0% | / | ≤0.2% | ≤0.3% | ≤1.0% |
| 34 | tBu-OOC-C14-CO-Glu-OtBu | NA | Insulin degludec Fragment I | ≥98.0% | ≤0.2% | ≤0.5% | ≤0.5% | ≤1.0% |
| 35 | tBu-OOC-C14-CO-Glu(NES)-OtBu | NA | Insulin degludec Fragment II | ≥96.0% | ≤0.5% | ≤1.0% | ≤1.0% | ≤1.0% |
SI *= Ho se hloeke ho itseng
Max*= Tšilafalo e Felletseng e sa Tsejoeng
Sesupo se seng:
- Acetic Acid: ≤0.02% (Lihlahisoa Tsohle)
- Ethyl Acetate: ≤0.5% (Lihlahisoa Tsohle)
- Joala: ≤0.5% (Lihlahisoa Tsohle)
Tlhoekiso ea bohloeki
Ho hloekisa tsamaiso ea kabo, ho kenyelletsa loop le tanka ea polokelo ho etsoa ke Pasteurization. Ha Pasteurization sanitization e etsoa, metsi a hloekisitsoeng ka tanka a futhumatsoa ho fihlela ho 80 ° C 'me a qala ho potoloha ka mokhoa oa ho aba. Tsamaiso ea likhoerekhoere e nka hora e le 'ngoe ka mor'a ho fihla ho 80°C. Tsamaiso ea likhoerekhoere e etsoa kotara e 'ngoe le e 'ngoe. Buka ea lintlha tsa tsamaiso ea likhoerekhoere tsa metsi a hloekisitsoeng e ile ea hlahlojoa ntle le leeto le totobalitsoeng.
